Foundations of Biological InquiryBIOL1101
The Foundations of Biological Inquiry course (BIOL1101) was developed by Dr. Manogaran in the Spring of 2013 as a way to bring undergraduate research experiences to talented and promising freshman biology students. Students were exposed to the basics of laboratory techniques and then developed a research project investigating how environmental stress impacts the propagation of the [PSI+] prion. All thirteen students presented their research at the Marquette University Biology Department Undergraduate Research Symposium in the Spring of 2014.
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Emily Nett and Elizabeth Young performing serial dilutions.
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Dr. Manogaran is currently working with Dr. Greg Smith at Lakeland College to expand "Prions in the Classroom" to undergraduate students at Lakeland College. This collaboration will bring undergraduate research experiences focused on prion biology to a large number of students who do not have access to research laboratories.
Melissa Mann and John LeClaire executing their experiment.
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Results from several groups on the impact of environmental stresses on prion propagation.
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Dr. Manogaran working with Emily Legan and Matthew Odishoo, calculating how many grams of caffeine will go into solution.
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SMART TEAMS
Students Modeling A Research Topic
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Dr. Manogaran has worked with the MSOE Center for Bimolecular Modeling for several years at a mentor for the SMART Team program. This innovative program brings concepts of the molecular world, such as protein folding, and structure/function relationships to high school students. Students design and print three-dimensional models of proteins associated with prion biology.
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Dr. Manogaran with the SMART team from St. Joan Antida, a private Milwaukee high school serving diverse young women. 2004.
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Dr. Manogaran has mentored high school students since 2004.
2004. St. Joan Antida High School.
The eukaryotic peptide chain release factor GTP-binding subunit (Sup35p). Misfolded conformations of this protein is associated with the [PSI+] prion.
2007. Bradford High School. Sis1p, the Hsp40 family chaperone associated with propagation of the [RNQ+] prion.
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2005. St Joan Antida High School.
The GNNQQNY peptide associated with Sup35p, associated with the prion fold of [PSI+].
2008. Community SMART Team. Seven amino acid region of Sup35p associated with prion conformations. 1YJP.db
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2006. Brown Deer High School. Several different folds associated with the Abeta protein. 1Z0Q.pdb
2011. Laconia High School.
The solenoid structure of the [Het-s] prion. 7KJ3.pdb
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Special thanks to CBM Director Tim Herman, former SMART Team Director Shannon Colton, and the staff at the Center for BioMolecular Modeling for making this program possible. The Manogaran lab is grateful for the all of your amazing work!
Underrepresented Students in STEM
Dr. Manogaran has held several externally funded programs (WisCAMP and UW-System) focused in engaging underrepresented students (women and minorities) in STEM at her former institution, UW-Milwaukee. These projects were designed to integrate strong mentorship and scientific research experiences for diverse students. Dr. Manogaran has also worked on developing Women in Science NSF-Advance proposals for both UW-Milwaukee and Marquette University.
TeachingUnderstanding and implementing effective methodologies that enhance student learning is at the forefront of teaching. Integrating active learning, aspects of flipped classroom, and inquiry based learning has been part of Dr. Manogaran's teaching.
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Courses previously taught:
- BIOL1001 – General Biology 1
- BIOL1410 – Biology of Human Diseases
- BIOL1101 – Foundations in Biological Inquiry
- BIOL2001 – Principles of Biological Investigation
- BIOL2301 – Neurobiology
- BIOL3501 – Cell Biology
- BIOL6005 – Scientific Writing
Student comments about Dr. Manogaran's teaching and mentorship:
Dr. Manogaran was one of the best educators I have ever learned from. Her class was one of the more challenging courses I took, but she was always available to clarify anything she taught. She was one of the few teachers I could say who truly cared about the success of her students.
Dr. Anita Manogaran has been my mentor since the end of my first semester at Marquette. To summarize in one sentence, I would say that her work ethic, commitment, and dedication to her research and students is inspirational.
Dr. Manogaran was one of the best educators I have ever learned from. Her class was one of the more challenging courses I took, but she was always available to clarify anything she taught. She was one of the few teachers I could say who truly cared about the success of her students.
Dr. Anita Manogaran has been my mentor since the end of my first semester at Marquette. To summarize in one sentence, I would say that her work ethic, commitment, and dedication to her research and students is inspirational.